Reticulocyte haem synthesis in occupational exposure to trinitrotoluene.

Reticulocyte haem synthesis in occupational exposure to trinitrotoluene.

Haem disorder in recombinant- and reticulocyte-derived haemoglobins: evidence for stereoselective haem insertion in eukaryotes.

We have used NMR spectroscopy to measure haem disorder in adult human haemoglobin (HbA) obtained from mature erythrocyte cells and from yeast expressing recombinant HbA. Reticulocyte-derived HbA contained much higher levels of haem disorder (11% alpha- and 28% beta-subunit disorder) than observed for HbA from mature erythrocytes (1.5% alpha- and 8% beta-subunit disorder). Thus, unlike in vitro ...

Occupational Exposure To

Cardiovascular adverse health effect of occupational exposure to Licorice dust

Introduction: Prolonged use of licorice is known to cause headaches hypertension cardiac arrhythmias edema lethargy shortness of breath sodium retention and loss of potassium in healthy people. However to best of authors' knowledge to date the potential adverse health effects of occupational inhalation exposure to licorice dust have not been examined. This study was therefore under look to ad...

Ferrioxamine iron in rabbit reticulocyte heme synthesis.

By M. D. GERLANC, E. J. ZAPOLSKJ, M. Rurnr r AND J. V. Pm aorro P ESFERRIOXAMINE, the sideramine of the Actinomyces, is a potent chelator of ferric iron.1’2 It is believed that all aerobic organisms produce sideramines which function as specific iron donors ( coenzymes ) for the iron incorporating enzyme of the heme synthesis.a.4 I,, light of the role of ferrioxanlines in henle synthesis in mic...